Dr Graeme Turnbull

Senior Lecturer

Department: Applied Sciences

Dr Graeme Turnbull is an Assistant Professor of Chemistry in the Department of Applied Sciences. His research is focused on collaboration with industry, and current projects include the development of novel methods for microbial diagnostics with bioMérieux, and a Knowledge Transfer Partnership in industrial biocatalysis with Sterling Pharma Solutions.

Campus Address

A111 Ellison Building
City Campus
Newcastle upon Tyne
NE1 8ST

Email Graeme

Key Publications

A concise synthesis of anti-bicyclo[6.1.0]nonyne carboxylic acid, Weir, M., Vaccari, B., Matthews, A., Turnbull, G., Kozhevnikov, V. 21 Nov 2024, In: RSC Advances
Chromogenic enzyme substrates based on [2-(nitroaryl)ethenyl]pyridinium and quinolinium derivatives for the detection of nitroreductase activity in clinically important microorganisms, Cellier-Rastit, M., Chalansonnet, V., James, A., Johnston, A., Orenga, S., Perry, J., Roger-Dalbert, C., Salwatura, V., Stanforth, S., Sykes, H., Truong, V., Turnbull, G. 14 Jul 2023, In: Journal of Materials Chemistry B
Beyond GalNAc! Drug delivery systems comprising complex oligosaccharides for targeted use of nucleic acid therapeutics, O'Sullivan, J., Muñoz-Muñoz, J., Turnbull, G., Sim, N., Penny, S., Moschos, S. 14 Jul 2022, In: RSC Advances
Evaluation of a Novel Chromogenic Medium for the Detection of Pseudomonas aeruginosa in Respiratory Samples from Patients with Cystic Fibrosis, Truong, T., Twist, A., Zaytsev, A., Marrs, E., Perry, A., Turnbull, G., Orenga, S., Stanforth, S., Perry, J. 10 May 2022, In: Microorganisms
Benzannulation via the use of 1,2,4-triazines extends aromatic system of cyclometallated Pt(II) complexes to achieve candle light electroluminescence, Pander, P., Turnbull, G., Zaytsev, A., Dias, F., Kozhevnikov, V. 1 Jan 2021, In: Dyes and Pigments
A Flexible Topo-optical Sensing Technology with Ultra-high Contrast, Wang, C., Wang, D., Kozhevnikov, V., Dai, X., Turnbull, G., Chen, X., Kong, J., Tang, B., Li, Y., Xu, B. 1 Dec 2020, In: Nature Communications
Fluorogenic L-alanylaminopeptidase substrates derived from 6-amino-2-hetarylquinolines and 7-amino-3-hetarylcoumarins and their potential applications in diagnostic microbiology, Cellier-Rastit, M., James, A., Orenga, S., Perry, J., Robinson, S., Turnbull, G., Stanforth, S. 15 May 2019, In: Bioorganic and Medicinal Chemistry Letters
Rigidly linking cyclometallated Ir(iii) and Pt(ii) centres: an efficient approach to strongly absorbing and highly phosphorescent red emitters, Turnbull, G., Williams, G., Kozhevnikov, V. 4 Mar 2017, In: Chemical Communications
The Synthesis of L-Alanyl and β-Alanyl Derivatives of 2-Aminoacridone and Their Application in the Detection of Clinically-Important Microorganisms, James, A., Cellier, M., Orenga, S., Perry, J., Turnbull, G., Stanforth, S. 8 Jul 2016, In: PLoS One
2-(Nitroaryl)benzothiazole and benzoxazole derivatives as fluorogenic substrates for the detection of nitroreductase activity in clinically important microorganisms, Cellier, M., Gignoux, A., James, A., Orenga, S., Perry, J., Robinson, S., Stanforth, S., Turnbull, G. 15 Dec 2015, In: Bioorganic & Medicinal Chemistry Letters

Professional Activity

Participating in a conference, workshop, ...: Enzyme Immobilisation - Industrial Opportunities & Implementation Challenges 2021
Invited talk: Industrial Biocatalysis: Routes to Organic Synthesis 2019
Oral presentation: Green Synthesis of Dibasic Acids using Biocatalysis 2018
Invited talk: Green Synthesis of Dibasic Acids using Biocatalysis - A Case Study 2017
Invited talk: Synthesis and applications of fluorescent heterocyclic enzyme substrates. 2016
Oral presentation: Discovery and development of a group 1 nitrilase for use in industrial biocatalysis. 2014
Invited talk: Novel heterocyclic fluorogenic substrates for the detection and identification of clinically-important microorganisms. 2011

PGR Supervision

Amy Garcha The synthesis and evaluation of novel chromogenic and fluorogenic enzyme substrates for the detection of microorganisms. Start Date: 20/05/2022
Audrey Perry Rapid Diagnostics In Clinical And Environmental Microbiology Start Date: 01/10/2021
Niamh Oliver Synthesis and evaluation of novel chromogenic and fluorogenic enzyme substrates for use in microbial diagnostics Start Date: 01/10/2022
Bernardo Santos Velosa Start Date: 01/10/2024

Qualifications

Chemistry PhD December 10 2012
Chemistry BSc (Hons) July 01 2009
Fellowship of the Higher Education Academy FHEA 2018
Chartered Chemist of the Royal Society of Chemistry CChem 2016
Chartered Scientist of The Science Council CSci 2016
Member of the Royal Society of Chemistry MRSC 2014

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